פרופ' יובל אבנשטיין

• Ph.D., Physical Chemistry, Hebrew University, Jerusalem, Israel, 2007

• Ms.S., Physical Chemistry, Hebrew University, Jerusalem, Israel, 2001

• BS.c., Physics and Chemistry, Hebrew University, Jerusalem, Israel, 2000

• Founder and Academic director, Tel-Aviv University, Entrepreneurship and Innovation Center, Tel-Aviv, Israel, 2018-Present

• Associate professor, Tel-Aviv University, Department of Chemical Physics, School of Chemistry, Tel-Aviv, Israel, 2016-Present

• Senior lecturer, Department of Chemical Physics, School of Chemistry, Tel Aviv University, Tel Aviv, Israel, 2011-2016

• The Raymond and Beverly Sackler Career Development Chair - 2014, 2013-2014

• Postdoctoral research fellow, under the supervision of Prof. Shimon Weiss, Department of Chemistry and Biochemistry, DOE Institute for Genomics and Proteomics – UCLA, Los Angeles, USA, 2006-2011

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1. Jonathan Jeffet (ST), Asaf Kobo (ST), Tianxiang Su (ST), Assaf Grunwald (ST), Ori Green (ST), Adam N. Nilsson (ST), Eli Eisenberg (ST), Tobias Ambjörnsson (CI), Fredrik Westerlund (CI), Elmar Weinhold (CI), Doron Shabat (CI), Prashant K. Purohit (CI), and Yuval Ebenstein* (PI), Super-Resolution Genome Mapping in Silicon Nanochannels. ACS Nano (2016), 10 (11), 9823–9830

2. Noa Gilat (ST), Tzlil Tabachnik (ST), Amit Shwartz (ST), Tamar Shahal (CI), Dmitry Torchinsky (ST), Yael Michaeli (CI), Gil Nifker (ST), Shahar Zirkin* (CI) and Yuval Ebenstein* (PI), Single-molecule quantification of 5-hydroxymethylcytosine for diagnosis of blood and colon cancers. Clinical epigenetics (2017), 9(1), 70. DOI:10.1186/s13148-017-0368-9.

3. Tslil Gabrieli (ST), Hila Sharim (ST), Dena Fridman (ST), Nissim Arbib, Yael Michaeli (CI) and Yuval Ebenstein* (PI), Selective nanopore sequencing of human BRCA1 by Cas9-assisted targeting of chromosome segments (CATCH). Nucleic Acids Research (2018),46, 14, e87.  DOI: 10.1093/nar/gky411.

4. Tslil Gabrieli (ST), Hila Sharim (ST), Gil Nifker (ST), Jonathan Jeffet (ST), Tamar Shahal (CI), Rani Arielly (ST), Michal Levy-Sakin, Lily Hoch, Nissim Arbib, Yael Michaeli (CI) and Yuval Ebenstein* (PI), Epigenetic Optical Mapping of 5-Hydroxymethylcytosine in Nanochannel Arrays. ACS Nano (2018), 12, 7, 7148–7158. DOI: 10.1021/acsnano.8b03023.

5. Hila Sharim(ST), Assaf Grunwald(ST), Tslil Gabrieli(ST), Yael Michaeli(T), Sapir Margalit(ST), Dmitry Torchinsky(ST), Rani Arielly(ST), Gil Nifker(ST), Matyas Juhasz, Felix Gularek, Miguel Almalve, Brandon Dufault, Sreetama Sen Chandra, Alexander Liu, Surajit Bhattacharya, Yi-Wen Chen, Eric Vilain, Kathryn R Wagner, Jonathan Pevsner, Jeff Reifenberger, Ernest T Lam, Alex R Hastie, Han Cao, Hayk Barseghyan, Elmar Weinhold*(PI) and Yuval Ebenstein*(PI), Long-read single-molecule maps of the functional methylome. Genome Research (2019) 29:646–656. DOI: 10.1101/gr.240739.118.

6. Nikhil Jain, Tamar Shahal(T), Tslil Gabrieli(ST), Noa Gilat(ST), Dmitry Torchinsky(ST), Yael   Michaeli(T), Viola Vogel and Yuval Ebenstein*(PI), Global Modulation in DNA Epigenetics during Pro- Inflammatory Macrophage Activation. Epigenetics (2019), 14, 12, 1183-1193. doi:10.1080/15592294.2019.1638700.

7. Dmitry Torchinsky(ST), Yael Michaeli(T), Natalie R. Gassman and Yuval Ebenstein*(PI), Simultaneous detection of multiple DNA damage types by multi-colour fluorescent labelling. Chemical Communications (2019), 55, 11414-11417. https://doi.org/10.1039/C9CC05198H.

8. Sapir Margalit(ST), Sigal Avraham(ST), Tamar Shahal(T), Yael Michaeli(T), Noa Gilat(ST), Prerna Magod, Michal Caspi, Shelly Loewenstein, Guy Lahat, Dinorah Friedmann‐Morvinski, Revital Kariv, Rina Rosin‐Arbesfeld, Shahar Zirkin(T)  and Yuval Ebenstein* (PI), 5‐hydroxymethylcytosine as a clinical biomarker: Fluorescence‐based assay for high‐throughput epigenetic quantification in human tissues. International Journal of Cancer (2020),146, 1, 115-122.  https://doi.org/10.1002/ijc.32519.

9. Noa Gilat(ST), Dmitry Torchinsky(ST), Sapir Margalit(ST), Yael Michaeli(T), Sigal Avraham(ST), Hila Sharim(ST), Nadav Elkoshi, Carmit Levy, Shahar Zirkin(ST), Yuval Ebenstein*(PI), Rapid Quantification of Oxidation and UV Induced DNA Damage by Repair Assisted Damage Detection-(Rapid RADD). Anal Chem (2020), 92, 14, 9887–9894. https:/doi.org/10.1021/acs.analchem.0c01393.

10. Christian Heck (PD), Dmitry Torchinsky(ST), Gil Nifker(ST), Felix Gularek(ST) , Yael Michaeli(T), Elmar Weinhold , Yuval Ebenstein*(PI) , Label as you fold: methyltransferase-assisted functionalization of DNA nanostructures. Nanoscale (2020), 12, 20287-20291 (2020). DOI: 10.1039/d0nr03694c.